Although E2F7 expression was not associated with age, tumor size, or lymph node metastasis, there was evidence of an association with histological grade (p < 0.001), lymph vessel invasion (p = 0.003), and depth of invasion of cervical stroma (p < 0.001) (Additional file 1: Table S1). The gene discussed is E2F7; the disease is metastatic malignant neoplasm in the lymph nodes.