As shown in Additional file 1: Table S1, E2F1 expression was significantly related to histological grade (p = 0.01), lymph node metastasis (p = 0.005), lymph vessel invasion (p = 0.029), and depth of invasion of cervical stroma (p < 0.001), whereas age and tumor size were not significantly associated (both p > 0.05). The gene discussed is E2F1; the disease is neoplasm.