YAP1 and neoplasm: Compared with the mice co-treated with antagomir NC and oe-NC, the average tumor volume and weight in mice co-treated with miR-21 antagomir and oe-NC were both decreased, compared with the latter, the average tumor volume and weight in mice co-treated with miR-21 antagomir and oe-YAP were both increased (p < 0.05) (Fig. 5a–c).