Compared with the mice co-treated with antagomir NC and oe-NC, the MDSCs in peripheral blood and tumor tissues of mice co-treated with miR-21 antagomir and oe-NC inhibited the proliferation of Th and CTL, while the opposite was true in MDSCs in peripheral blood and tumor tissues of mice injected with miR-21 antagomir and oe-YAP compared with mice treated with both miR-21 antagomir and oe-NC (p < 0.05) (Fig. 3g–h). The gene discussed is YAP1; the disease is neoplasm.