TMPRSS2 was differentially expressed in kidney renal clear cell carcinoma (KIRC), kidney renal papillary cell carcinoma (KIRP), lung squamous cell carcinoma (LUSC), colon adenocarcinoma (COAD), uterine corpus endometrial carcinoma (UCEC), head and neck squamous cell carcinoma (HNSC), lung adenocarcinoma (LUAD), BRCA, PRAD and LIHC and IFITM3 was differentially expressed in COAD, KIRC, KICH, HNSC, LUSC, STAD, esophageal carcinoma (ESCA), THCA, LIHC, BRCA and PRAD (Figure 3D). The gene discussed is TMPRSS2; the disease is colon adenocarcinoma.