While we found no difference in S. Typhimurium burden in the MLN and caecum of Il22Ra1fl/fl;Defa6-cre+ and their littermate cre- mice, we observed increased S. Typhimurium dissemination in the liver of Il22Ra1fl/fl;Defa6-cre+ mice on day 4 post infection (Fig. 7f). The gene discussed is DEFA6; the disease is infection.