IFIH1 and infection: Like RIG-I expression, MDA5 expression was activated at the acute infection stage from 1 to 7 dpi (42.69 ± 22.97-fold higher than pre-infection, p = 0.8644), inhibited during pregnancy (8 dpi to delivery, 10.85 ± 9.81-fold, p = 0.4955), and increased by 38.50 ± 51.40-fold (p = 0.4308) once the baby was born (Fig. 5B).