IFNA1 and rheumatoid arthritis: HBEGF+ proinflammatory macrophages and phagocytic macrophages tended to be more enriched in RA patients, although not uniformly, whereas quiescent and IFN-activated macrophages were more enriched in LA, the latter population reaching statistical significance (see Supplementary Fig. S9 online; p = 0.00857)10,11.