Parenthetically, the two ICRs in this region, the H19/IGF2 ICR (chr11: 2,018,812–2,024,740) and KvDMR1 (chr11: 2,719,948–2,722-259), each displayed approximately equal percent methylation in beta cells (49.5% and 41.9%, respectively) and insulinomas (47.9% and 36.5%, respectively). The gene discussed is KCNQ1OT1; the disease is pancreatic insulinoma.