In a phase I/II study, GO (2 mg/m2) as part of a preparative regimen for allogeneic HSCT was considered safe in patients with high-risk CD33 + AML, CML, or myelodysplastic leukemias, with 1 case of VOD/SOS among 52 patients [25]. The gene discussed is CD33; the disease is acute myeloid leukemia.