Despite the broadening fund of knowledge regarding the action of TUG1 and miR-29c-3p in the regulation of angiogenesis, and despite the growing body of evidence to suggest that impaired angiogenesis is involved in the pathophysiology of DFS, little is known regarding the role of TUG1 and miR-29c-3p in EPC function in diabetes. This evidence concerns the gene TUG1 and diabetes mellitus.