PNPLA3 and metabolic dysfunction-associated steatotic liver disease: Although the presence of the G allele in the PNPLA3 rs738409 gene polymorphism was associated with a greater reduction in metabolic parameters, including intrahepatic triglycerides, body weight, the waist-to-hip ratio, blood total cholesterol, and low-density lipoprotein levels, there was no significant difference in the remission of NAFLD among patients with different PNPLA3 rs738409 genotypes [32].