TGIF1 and acute myeloid leukemia: Indeed, our data showed a twofold higher frequency of LICs in Tgif1−/− mice with AML (1 in 125) (95% CI, lower: 1 in 279 and higher: 1 in 56.5) than in Tgif1+/+ mice (1 in 250) (95% CI, lower: 1 in 603 and higher: 1 in 103.6).