While chemotherapy treatment extended survival of both Tgif1+/+ and Tgif1−/− mice with AML (compare Figure 3B to Figure 2D), mice transplanted with Tgif1−/− leukaemia cells still had shorter survival than mice transplanted with Tgif1+/+ leukaemia cells (Figure 3B). Here, TGIF1 is linked to acute myeloid leukemia.