These results corroborate the enhanced TGF‐β signalling and/or target gene expression noted in epithelial 6 and myeloid leukaemia cells 11 with diminished TGIF1 expression, and align with roles for TGF‐β in HSC self‐renewal,21 quiescence 22 and enhanced leukaemic stem cell function.21, 35. Here, TGIF1 is linked to myeloid leukemia.