The role of LOX as a potential predictive factor in cancer metastasis and progression was evidenced in several human cancers, such as pancreatic carcinoma,31 gastric carcinoma,32, 33 hepatocellular carcinoma (HCC),34 lung adenocarcinoma,35 breast cancer,36, 37 and cervical cancer.38 The gene discussed is LOX; the disease is breast carcinoma.