LEF1 and colorectal carcinoma: Restoration of full-length APC in APC mutant CRC cells reduces β-catenin/TCF/LEF1 signalling [7, 9] and in SW480 cells the expression of full-length APC leads to functional adhesion junctions, reduced colony growth in soft agar and the SW480-APC cells no longer grow as xenografts in mice [7].