RASSF1 and nasopharyngeal carcinoma: We also performed a rescue assay in RASSF1A-depleted NPC cells with transient knockdown of YAP1 and demonstrated that ectopic PDGF-BB treatment restored the inhibition of YAP1 knockdown-mediated malignant phenotypes, confirming that PDGFB is directly downstream of the RASSF1A/YAP1 axis.