To further investigate the involvement of YAP1 in linking RASSF1A with PDGFB, we transiently knocked down YAP1 by using a pool of mixed siRNA in RASSF1A-depleted NPC cells, as confirmed by western blot analysis (Fig. 5a), and downregulated CTGF and CYR61, a hallmark of YAP1 activation as confirmed by qRT-PCR (Fig. 5b). The gene discussed is PDGFB; the disease is nasopharyngeal carcinoma.