For the SIRT1 gene, 6 predicted miRNAs have previously been reported to have a clear relationship with HD (miR-22-3p, miR-138-5p, miR-9-5p, miR-132-3p, miR-135b-5p, and miR-135a-5p) [24, 25], and 1 miRNA for the SUZ12 gene (miR-19b-3p) [26]. Here, SIRT1 is linked to Huntington disease.