SAT1 and cerebellar ataxia: The α-Synuclein levels were also elevated in the cerebrum of Smox/Sat1-dKO at 8 (mild ataxia) and 14+ (severe ataxia) weeks of age (Supplemental Fig. 6), but their expression levels were lower in comparison to those found in the cerebellum of the same animals (Fig. 8a).