Resveratrol has multiple targets in cancer cells, such as cyclooxygenase (COX)/lipoxygenase (LOX), tyrosine kinase (p56lck), protein kinase C (PKC), protein kinase D (PKD), mitogen-activated protein kinase (MAPK), extracellular signal-regulated kinase (ERK)1/2, stress-activated kinases c- Jun N-terminal kinase 1/2, p38 MAPK [99], and adenylyl cyclase. This evidence concerns the gene PRKD1 and cancer.