No difference observed in the cross‐sectional area of muscle fibres, protein concentration per unit of DNA, and muscle strength. No difference observed in the proteins of the Akt/FOXO pathway and of the UPS (including MuRF1 and MAFBx). Regarding the autophagic–lysosomal system, increased protein expression of BNIP3 in CC vs. CNC patients, no difference observed for LC3B. No difference observed for luciferase activity of NF‐κB, and for mRNA expression of IκBα (NF‐κB inhibitor). The gene discussed is BNIP3; the disease is Carney complex.