SFRP2 and leprosy: In another leprosy biopsy, we observed a population of pro-inflammatory fibroblasts (fibroblast cluster 5) that expresses elevated amounts of SFRP2, PRSS23, and IL6. Finally, among all 5 psoriasis biopsies, we observed a population of pro-inflammatory fibroblasts (fibroblast cluster 4) marked by elevated expression of CCL19, TNFSF13B (BAFF), and CXCL12 (Figures 5H–5I; Table S3).