HAVCR1 and chronic kidney disease: Given the literature supporting strong associations between both tubular injury and oxidative stress biomarkers and CKD progression and/or renal function, the observed changes in NGAL and KIM-1 and 8-OHdG and F2-isoprostane in relation to BPA and phthalates raise concerns about the potential for clinically significant alterations in chronic kidney function to emerge in the long term.