MCL1 and gastric cancer: This is the first study to illustrate the roles of Mcl-1L and Mcl-1S in GC systematically and verify the therapeutic effects of the modulated Mcl-1 splicing pattern in this disease; up-regulated Mcl-l L and down-regulated Mcl-1S expression in AGS cells, a human gastric adenocarcinoma epithelial cell line, has been previously demonstrated [29].