PD-L1 expression is more frequent in SCC than adenocarcinoma in cervical cancer (54% v 14%) and non–small-cell lung cancer (52% v 17%).29,30 Given that higher PD-L1 expression has been associated with better outcomes of anti–PD-1/PD-L1 treatment, we suspected that the higher PD-L1 expression in SCC may to some extent contribute to the better response in this subgroup. This evidence concerns the gene CD274 and lung cancer.