Seibert et al. in adult patients diagnosed for CKD in the course of the following diseases: diabetes mellitus, hypertensive nephropathy, glomerulonephritis and autosomal dominant polycystic kidney disease, did not confirm the better usefulness of NGAL and KIM-1as prognostic factors in comparison with standard albuminuria [12]. This evidence concerns the gene LCN2 and hypertensive nephropathy.