High SLC14A1 protein levels were correlated with early primary tumor status (P < 0.001), negative nodal metastasis (P < 0.001), low histological grade (P < 0.001), negative vascular invasion (P < 0.001), negative perineural invasion (P < 0.05) and low mitotic rate (P < 0.01) in two large cohorts of UTUC (n = 340) and UBUC (n = 295) patients (Supplementary Table S3). The gene discussed is SLC14A1; the disease is renal pelvis/ureter urothelial carcinoma.