SLC14A1 and neoplasm: In mouse xenograft experiments, the average tumor size at day 14 after transplantation was smaller in SLC14A1-overexpressing UMUC3 cells than in the mock (P < 0.05), while it was restored to the similar size as the mock in xenografts from SLC14A1(C25S/C30S)-overexpressing cells (Figure 3I).