DNTT and Sepsis: Histopathological analysis of kidney tissues from mice at 72h after CLP showed the DAPK1-i-injected mice presented a significantly reduced number of cells positive for TdT-mediated dUTP nick end labelling (TUNEL) staining, an indicative of apoptotic response, and cells positive for neutrophil gelatinase-associated lipocalin (NGAL), an index of renal injury, compared to the PBS-injected or si.Ctrl-delivered mice (Figure 6B), respectively, suggesting that deactivation of DAPK1 allows mice resistant to the sepsis-initiated AKI.