When comparing the clinical characteristics of the 8 groups, we found that the following parameters showed significant differences: age, the proportion of men, SBP, durations of the disease, disease onset age, smoking and drinking, Hb levels, FBG levels, HbA1C levels, Alb levels, TC levels, LDL-C levels, proteinuria, uric acid levels, eGFR, HOMA2-B, DR, DPN, DN, DK, CHD, CVD, HTN, ARB, lipid-lowering agents, OHA, and insulin (P < 0.05). The gene discussed is GSTM1; the disease is hypertensive disorder.