However, when comparing the tumours of T1a and T1b stage (it would not be reasonable to analyse other T stages due to the low number of cases in each group), there was a significant difference in the H-score between these two stages, with T1a tumours showing a higher HNF1B expression than T1b tumours (pT1a: mean = 235.8, median = 280; pT1b: mean = 181.0, median = 185, p = 0.046; data not shown in Table 2). This evidence concerns the gene HNF1B and neoplasm.