PPARɣ ligands, including 1-(trans-methylimino-N-oxy)-6-(2-morpholinoethoxy)-3-phenyl-(1H-indene-2-carboxylic acid ethyl ester) (KR-62980) and rosiglitazone, exert anti-lung cancer effects by inducing ROS production, apoptosis, and differentiation and by inhibiting cell viability37. The gene discussed is PPARA; the disease is lung cancer.