Interestingly, among >1400 cancer cell lines, the expression of WNK1 is highest in T-cell acute lymphoblastic leukemia (T-ALL) lines, many of which originate from immature thymocytes (Cancer Cell Line Encyclopedia, CCLE https://portals.broadinstitute.org/ccle) (Barretina et al., 2012; Tan et al., 2017). This evidence concerns the gene WNK1 and cancer.