We assumed that miR-1246 might target UBE2C, TNNT1, TRAIP, and UCHL1 during the regulation of ubiquitin-mediated proteolysis, glycosaminoglycan binding, DNA metabolism, the PI3K–Akt–mTOR signaling pathway, the neurotrophin and cardiomyopathy signaling pathway, and the MAPK signaling pathway. This evidence concerns the gene UCHL1 and cardiomyopathy.