In migratory, invasive breast cancer, MIAT/DNMT1/DNMT3A/DNMT3B complexes suppress the HIPPO signaling pathway by downregulating discs large MAGUK scaffold protein 3 (DLG3) transcription level via recruitment to the DLG3 promoter region, and it thereby increases the translocation of yes-associated protein 1 (YAP) into the nucleus [62]. The gene discussed is YAP1; the disease is invasive breast carcinoma.