This may be important clinically, with lower expression levels of miR-29c, miR-148a, miR-148b, miR-26a, miR-26b, and miR-203 demonstrated to contribute to DNMT3b overexpression in hypermethylated breast cancer cell lines (Hs578T, HCC1937 and SUM185). Here, DNMT3B is linked to breast carcinoma.