In addition, we observed that A549 Hx EVs were enriched in the golgi-expressed glycosylation enzyme alpha 6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B (MGAT5B) which is a critical regulator of cancer cell–cell contact, EMT, and metastasis [52]. The gene discussed is MGAT5B; the disease is cancer.