Keap1: Kelch-like ECH-associated protein 1; Nrf2: Nuclear factor erythroid 2 p45 (NF-E2)-related factor; sMaf: Small musculoaponeurotic fibrosarcoma protein; ARE: Antioxidant response element; GSH: Glutathione; SOD: superoxide dismutase; CAT: Catalase; GPx: Glutathione peroxidase, FA: fatty acid; AA: Amino acid; NADPH: nicotine adenine dinucleotide phosphate; TCA: tricarboxylic acid. Here, KEAP1 is linked to fibrosarcoma.