Keap1: Kelch-like ECH-associated protein 1; Nrf2: Nuclear factor erythroid 2 p45 (NF-E2)-related factor; sMaf: Small musculoaponeurotic fibrosarcoma protein; ARE: Antioxidant response element; GSH: glutathione; SOD: superoxide dismutase; CAT: Catalase; GPx: Glutathione peroxidase. Here, NFE2 is linked to fibrosarcoma.