In a study of 41 NB tumors analyzed by IHC (7 MYCN-A and 34 MYCN-NA), a higher presence of α-SMA-positive, non-pericytic (h-Caldesmon-negative) CAFs in MYCN-A tumors vs. MYCN-NA tumors, was reported [29]. The gene discussed is ACTA1; the disease is neuroblastoma.