AURKA and neoplasm: Because the EGFR mutations enrolled in the current study (i.e., L858R expression and Exon 19 in-frame deletion) alter tumor progression and deterioration in LADC [8,38,39], a reduced occurrence of AURKA SNP rs1047972 in the population indicates that AURKA SNP rs1047972 has similar genetic variations to that of EGFR mutations, which merits further evaluation.