GLIS2 and acute myeloid leukemia: According to the reported myeloid NKL-code, six NKL homeobox genes participate in the physiological differentiation of granulocytes (basophils, eosinophils, neutrophils), monocytes and macrophages, dendritic cells, and erythrocytes while 24 deregulated members of the NKL subclass are described in AML and MDS [18].