These studies have included not only the well‐known IDH1 mutation status, but also some factors discovered in recent years by bioinformatics analysis, such as eukaryotic initiation factor and some N6‐methyladenosine (m6A) RNA methylation regulators3, 4; however, according to the 2016 WHO brain tumor classification, IDH1 mutation status and 1p/19q are the only universally recognized significant prognostic biomarkers of LGG.5 The gene discussed is IDH1; the disease is brain neoplasm.