The association of immunoglobulin G (IgG) autoantibodies directed against myelin oligodendrocyte glycoprotein (MOG) to different disease entities has been discussed1, 2: MOG‐IgG was initially described in multiple sclerosis (MS), neuromyelitis optica spectrum disorders (NMOSD), relapsing inflammatory optic neuritis (RION), acute demyelinating encephalomyelitis (ADEM), or limbic encephalitis.3, 4, 5, 6, 7, 8, 9. This evidence concerns the gene MOG and multiple sclerosis.