Meanwhile, following miR‐223 up‐regulation or TRAF6 down‐regulation, expression of NLRP3 inflammasome‐related components (NLRP3, ASC and Caspase‐1) was reduced (Figure 4G), mouse body weight was elevated (Figure 4H), survival rate was increased (Figure 4I), myocarditis was inhibited in mice (Figure 4J,K), and LVEF and LVFS rose in VMC mice (Figure 4L,M). This evidence concerns the gene TRAF6 and myocarditis.