In addition to MEG3, several other oncogenic lncRNAs have also been determined to regulate the NF‐κB pathway, including lncRNA HOX transcript antisense RNA (HOTAIR) promoting TNF‐α production in LPS‐treated cardiomyocytes47 and lncRNA H19 promoting atherosclerosis mediated by MAPK.47 This evidence concerns the gene NFKB1 and atherosclerosis.