In the multivariable analysis obtained with clinical and CT parameters, significant predictors of the outcome were age > 61 years (OR 3.62; p < 0.001), ALT > 29.0 IU/L (OR 2.76; p < 0.001), emphysema volume > 0.10% (OR 2.73; p < 0.01), residual healthy lung parenchyma volume ≤ 70.20% (OR 3.54; p < 0.001) and consolidation volume > 1.40% (OR 3.19; p < 0.01). The gene discussed is GPT; the disease is pulmonary emphysema.