E2F8 and thyroid gland papillary carcinoma: In papillary thyroid cancer (PTC), miR-144 can directly target E2F family function as transcription factor 8 (E2F8) to significantly inhibit proliferation of PTC cells by inducing G1/S arrest via down-regulating CCND1, indicating that the miR-144/E2F8/CCND1 pathway may represent a potential therapeutic strategy for PTC 59.