CEACAM5 and neoplasm: Low albumin level (HR=0.952, 95% CI: 0.914-0.992, P=0.019), nerve infiltration (HR=2.740, 95% CI: 1.396-5.376, P= 0.003), tumor deposit (HR=3.236, 95% CI: 1.738-6.026, P<0.001), higher pre-treatment CEA level (HR=1.004, 95% CI: 1.000-1.007, P=0.039) were independent unfavored predictors for disease free survival (Table 4).