Multivariate analysis showed that low albumin level (HR=0.937, 95% CI: 0.893-0.983, P=0.007), nerve infiltration (HR=4.160, 95% CI: 1.176-14.718, P= 0.027), tumor deposit (HR=3.851, 95% CI: 1.094-13.552, P=0.036), higher post-treatment CEA level (HR=1.042, 95% CI: 1.017-1.067, P=0.001) were independent unfavored predictors for overall survival. Here, CEACAM5 is linked to neoplasm.