NPPB and cardiovascular disorder: However, for both sexes, there was no difference between responder and non-responder groups, regarding baseline parameters including age, BMI, blood pressure, proportion of diabetes mellitus, hyperlipidemia, current smoker, and baseline cardiovascular disease, LDL cholesterol, HDL cholesterol, hemoglobin A1c, white blood cell number, hemoglobin, etc. Furthermore, various biomarker levels at baseline including plasma BNP, UACR, eGFR, high molecular weight adiponectin, total adiponectin, and urinary 8-OHdG were similar between the groups, for either sex.