AKT1 and leukocyte adhesion deficiency: In this current study, we profile global lncRNA expression in activated AKT-overexpressing LAD cell lines with significantly potentiated metastatic abilities irrelevant to EMT process and identify an intergenic cytoplasmic lncRNA VAL (LINC01546, ENSG00000228459), which is induced by activated AKT via STAT3 transcriptional activity and correlates with disease progression and poor outcomes of LAD, as a potent pro-metastatic molecule.