Moreover, α-SMA (a pericyte marker) staining and dextran leakage assay demonstrated remarkedly increased perivascular coverage and reduced dextran leakiness in PyMT;Zeb1cKO tumors (Fig. 6f, g), revealing a critical role for Zeb1 in the maintenance of tumor vessel normalization and vascular integrity33. The gene discussed is ZEB1; the disease is neoplasm.