Five days of IL-13 treatment strongly downregulated ACE2 apical staining (2.4-fold, p = 0.03, Fig. 5b, e and Supplementary Fig. 3b), which was conversely strongly increased by both acute HRV-A (2.0-fold, p = 2e−3, Fig. 5c–e and Supplementary Fig. 3c) and HRV-C infection (1.7-fold, p = 0.02, Fig. 5e). This evidence concerns the gene IL13 and infection.