In this study, we used to explore the relationship between CYP1A1 and CYP1A2 genetic variants and the incidence of stroke in the Chinese population by the chi-square test and logistic-regression analysis, to provide theoretical basis for the function of CYP1A1 and CYP1A2 in stroke, and to provide more evidence for elucidating the cause of stroke. Here, CYP1A1 is linked to stroke disorder.