MG were then purified on CD11b-coated beads and treated with proinflammatory LPS for 2 h in the absence or presence of either dexamethasone (Dex; a synthetic GC) or IFN-β, the two compounds clinically used to alleviate neuroinflammation in MS, followed by expression profiling using RNA sequencing (RNAseq). The gene discussed is ITGAM; the disease is myeloid sarcoma.