Such as B cells naive, B cells memory, plasma cells, T cells CD8, T cells CD4 memory resting, T cells CD4 memory activated, T cells follicular helper, T cells regulatory (Tregs), T cells gamma delta, NK cells resting, Monocytes, Macrophages M0, Macrophages M1, Macrophages M2, Dendritic cells activated, Dendritic cells resting and Mast cells resting were markedly different between normal and tumor group, Just NK cells activated, Mast cells activated, Eosinophils and Neutrophils were not obviously changed between two groups. The gene discussed is CD4; the disease is neoplasm.